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HIV Life Expectancy Increases and Gives Hope to the Medical Community
Increased Life Expectancy for Individuals with HIV
There is good news on the horizon from research done over the life expectancy of HIV-positive patients. It was not too long ago that a diagnosis with HIV meant a drastically shortened life span; therapies, treatments and other variables have, however, slowly been developing over the past few years, making a drastic impact on the health and overall well being of those living with HIV. Information culled from studies over the past decade now paints a positive picture of the present and a hopeful one for the future.
Over 10 years ago, a study followed 23,000 HIV-positive individuals of Canadian and American backgrounds. Researchers tracked the life expectancy of each as the years passed. All participants were being treated with antiretroviral therapy (or ART) and were over 20 years old. Past clinical and social information were also gathered to see what bearing this would have on one’s mortality. Factors such as drug abuse, other illnesses and the time ART was started were all taken into consideration. The results were positive: In general, those being treated with ART for HIV were showing to have a life expectancy catching up to that of the general public.
10 years ago, the life expectancy of an HIV-positive person was around 50 years. Today, however, it is at nearly 70 years or greater. A healthy lifestyle, such as one devoid of drug abuse, is one reason for this increase. Another major factor is beginning ART early on, particularly when viral counts are lower. Both these things combined greatly increase one’s chances of living a full and healthy life. Advancements are being made and payoffs are beginning to show, with the future looking up for those who are HIV positive.
HIV and Secondary Health Conditions Prolong Hospital Stays, Incurring More Cost
HIV and Secondary Conditions Lengthen Hospital Stays
With medical costs on the rise, reducing hospital stays and expenses are in the best interests of all involved. Researchers decided to investigate how hospital stays differ for those who have HIV and secondary conditions. In an effort to organize and better manage time and resources, a study was conducted on the length, cost and complications of certain hospital stays. The results could help medical institutes come up with ways to better care for their patients, especially those with multiple medical issues.
In particular, HIV patients with secondary conditions—those that could become critical—were observed because their stays differed from those of the other patients. These were then broken down into categories, depending on infirmity. Conditions such as mental illness, obesity, hypertension and diabetes were looked at, with particular focus on the first. The reason for this special attention was that research showed that up to 50 percent of HIV patients also suffer from some form of mental illness.
The statistic has to do with the patients’ average age. Unfortunately, patients with HIV were much younger than those without HIV, with the difference being nearly a decade. Next, of the patients with HIV admitted to the hospital with a secondary condition, 7 percent died in the hospital. The time spent admitted in the hospital was 60 percent greater with HIV patients. The cost was much higher, too—over 75 percent more, in fact, than patients with no HIV infection.
These numbers show that education, reorganizing and planning may be necessary to reduce some of these numbers. This would mean that patients with HIV and secondary conditions might be able to reduce the amount of time spent in the hospital, thus reducing costs too. Awareness of the needs and severity of illness of HIV patients benefits not only the patients themselves but will help focus resources for medical institutions as well.
Kidney Transplants Also at Risk for HIV Infection in HIV-Positive Patients
Kidney Transplants at Risk for HIV Infection for HIV Patients
A large percentage of patients that are HIV positive will at some point deal with kidney damage or failure. It is for this reason that at least 1000 kidney transplants are needed for HIV-positive patients. HIV infection can target kidney functions, and at times, the transplant is rejected or also becomes infected with the virus. For the most part, a transplant in an HIV-positive patient is successful, but the percentage of those rejected is higher than for those who aren’t HIV positive. One medical institute decided to look into why this was this case.
From 2006 to 2011 a study was conducted on 19 patients who were both HIV positive and had kidney transplants. The findings were dramatic, as 68 percent of the transplants became infected with HIV. The number came as a surprise because some of the patients had little to no viral load evident in their blood. Those with undetectable levels of the virus were of particular interest: Even with no trace of infection—thanks to regular antiretroviral treatment—the HIV made its way into the new organ. Next, researchers found one of two types of infection in the kidney. The first one involved podocyte cells and other tubular cells, which each manifesting differently. In particular, podocyte cells in the kidneys, which are the cells involved in the process of filtering the blood, were a target for the HIV. Kidney dysfunction is one of the clinical signs of this type of infection, while the other kind of infection is more inconspicuous.
During the trial, a new way to identify kidney infection was developed. The process involved examining patients’ urine. This made it easier for participants to be tested. The results of this study will hopefully bring about ways to reduce organ rejection and infection, and improve the overall results of kidney transplants in HIV patients.
HIV Directly Linked to Heart Disease
HIV and Heart Disease
HIV and heart disease seem to go hand in hand. It’s very common for an HIV-positive person to present with some form of cardiac disease. Just why this is and how it happens, however, has remained somewhat of a mystery. In order to help clarify why this is so, a study was conducted to see if HIV and the heart were actually related or if it was all just coincidental.
One theory as to why heart diseases such as hypertension and HIV are commonly seen together is that HIV tends to trigger an inflammatory response. This adversely affects the vascular system when it becomes a chronic issue. In order to gauge the factors that contribute to this, a study followed 65 HIV-positive patients. All participants had shortness of breath to some degree, and each was given an echocardiogram to determine his or her cardiac functions. After the tests and other risk factors were taken into consideration, it was noted that nearly half of the participants had some form of cardiac dysfunction or disease.
A review of the findings revealed some interesting pieces of information. Gender, age and whether or not AIDS was present had little to no effect on the level of cardiac dysfunction a patient had. The variable that seemed the most conclusive involved the amount of viral load in the blood. Patients with a high viral load were those with the most progressive level of heart disease. Those who had limited or undetectable traces of infection fared much better. The latter presented with no disease, or with heart disease that was just at the beginning stages.
Conclusive evidence exists that HIV, especially one presenting a high viral load in the blood, is directly related to the presence of heart disease. Armed with this knowledge, the medical community can, therefore, screen patients with HIV for heart disease and use viral load as an indicator for the probability of the development of cardiac dysfunction.
HIV Patients Benefit Greatly From Taking Vitamin Supplements
Vitamin Supplements to Help HIV Patients
Taking vitamin supplements is part of a daily routine for many. However, when it comes to the immune system and HIV, they may also play a crucial role. Scientists have conducted long-term studies that show a marked improvement in the immune response of those with early signs of the virus.
There are certain nutrients imperative to the functioning of a healthy immune system. When that immune system is compromised such as by disease, those vitamins become even more vital. Research has indicated that a deficiency in the micronutrients that aid the immune system can be harmful. A deficiency in several nutrients could normally be found in patients who had yet to experience HIV symptoms, with the most significant deficiencies being those of selenium and vitamins B, E and C.
A study in Botswana followed over 800 HIV patients over the period of a couple years. The participants were divided into three main groups: A placebo group, one group that received all the nutrients in supplement form as mentioned above and finally one group on just a few select vitamins. All patients received this care prior to the start of antiretroviral therapy.
The results yielded showed the supplements to be beneficial. For one, blood tests remained at respectable levels; another benefit was the slowing down of the progression of the disease process. With a fortified immune system, symptoms manifested at a slower rate than without the supplements. Even though the study was conducted on patients in the very early stages of HIV, there was still a lower morbidity rate among those taking the vitamins and selenium. With this being an early treatment option that is both accessible and affordable, researchers are hopeful: This is one type of therapy that can be implemented quickly and which reduces the financial burden of treatment, especially in some poorer regions.