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Spike in HIV

Spike in HIV: Testing Climbs Because of Face-to-Face Social Networking

One of the biggest concerns in the battle against the spread of HIV is not being aware that one is infected. This is the leading reason for HIV’s continuing spread in developed countries, like the United States of America. In fact, as many as one in five people who are infected with HIV are asymptomatic and completely unaware of the infection. Because of this, they usually continue in the high-risk activities that exposed them to HIV in the first place (i.e. men who have sex with men, sharing drug utensils, etc). Traditional counseling, training, and referral (CTR), are the current mainstream programs designed to spread awareness of HIV and prompt people to get tested. However, these usually yield minimal results (less than one percent of those tested in this manner are shown to be HIV positive). A new form of face-to-face social networking, however, has resulted in a spike in HIV among high-risk individuals. That is, more HIV infected individuals have been found, not that HIV has actually increased in the populations at the highest risk of contracting the disease. What has been behind this success in finding HIV-positive individuals?

Social network strategies (SNS) programs, focusing on high-risk environments that encourage people to refer their friends and acquaintances (with a small monetary reward for each tested referral), has yielded a roughly 2.5 percent increase in positive tests. These programs proactively find high-risk environments and the people within them, as opposed to the CTR programs, which passively foster testing. SNS programs actively prompts those with HIV-positive and unaffected alike to recruit others they know to be involved in the various high-risk activities commonly associated with HIV infection. Of course, some worry about the cost of rewarding individuals for ever reference that gets tested. Indeed, there has been a minimal amount of “abuse” of gaining a monetary reward for each tested referral (roughly $10-20 per tested referral). However, others feel that the spike in HIV found among high-risk people is worth this price, and that it will be more cost effective overall. For example, a study of SNS programs and testing methods illustrates that the 30th or 40th person referred for testing through SNS had just as high (if not a higher) probability of being HIV positive, as did the first five or ten people referred in this manner. Certainly, more people being aware of being HIV positive, and at an earlier stage of the infection, means more are able to seek earlier treatment. Indeed, it is very important for HIV infected patients to get onto the life-saving anti-retroviral regimen as early as possible. Doing so will suppress the virus and prevent the progression to AIDS.

HPV and Increased HIV Risk Linked

Human papillomavirus, or HPV, has been linked to several genital cancers. These infections are particularly troublesome in countries where poverty and HIV are also rampant. Vaccines that protect against HPV infection have proven effective but certain threats still exist.

Moreover, this type of infection has been studied extensively in women, but limited attention has been given to its effects in men. A five-year study of HPV links this disease to an increased risk for HIV in men.

The tragic fact is that in certain places, like Kenya, the leading cause of death is HIV and AIDS. A study of over 2,500 Kenyan men was conducted to see if there was a connection between an infection caused by HPV and the risk of HIV infection. 61 of the men observed in the study had acquired HIV at some point during the trial. Unfortunately, there was a link: It was found that those who had HPV were at greater risk for acquiring HIV, and this proved true whether or not the male was circumcised. This comes as sad news: Each year, HIV claims nearly 2 million lives worldwide. The information gathered in this study showed that greater attention to the prevention of these diseases still has to be made.

One glimmer of hope is inoculation. As mentioned, there is a single-dose vaccine available for HPV, and it is useful in preventing HPV-borne cancers. Extensive research still has to be done to determine if this alone is enough to prevent HIV as well. The effects of the HPV vaccine and the results of administering it to men still have to be studied. However, it is still highly recommended for women to receive the vaccine.

Effective Prevention for HIV in Women

The sad facts point to a rise in the number of women who are infected with HIV. When compared to men, the percentage is remarkably higher. Even with modern treatment and certain preventative measures and therapies, the number of female victims is climbing. The problem lies in the economic state that many patients find themselves in, and certain cultural differences can also inhibit the use of certain therapies and prevention. Many patients stop or are inconsistent with their treatment as a result.

A recent development could help slow the progress of the virus by preventing spread of infection. With this information in mind, researchers are thrilled with the effectiveness of an intravaginal ring that contains an antiretroviral pharmaceutical. In tests that have been conducted in primates, the success rate was 100% in preventing transmission of the virus.

Besides its success in the lab, there are other advantages that researchers are hoping will prove beneficial. For example, the ring can last up to 30 days.  There is a lesser amount of the drug in the ring than would be needed if taken orally in pill form. This helps to reduce cost and hassle, a great benefit to the majority of women needing treatment. The amount of antiretroviral drug that it administers increases, rather than decreases, over that period of time. This is due to the type of polymer used to make the ring. It expands in fluid, thus administering the drug in adequate levels while inside the patient.

Human trials are underway and researchers and physicians are hopeful. In time, adding other drugs, such as those used in the prevention of STDs and even contraceptives is a possibility. This would further widen the ring’s appeal and encourage consistent usage. For now, researchers await the human trials with high expectations.

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